Blar i forfatter "Zhang, Zuobing"

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    • Immunostimulant Bathing Influences the Expression of Immune- and Metabolic-Related Genes in Atlantic Salmon Alevins 

      Figueiredo, Filipe; Kristoffersen, Harald; Bhat, Shripathi; Zhang, Zuobing; Godfroid, Jacques; Peruzzi, Stefano; Præbel, Kim; Dalmo, Roy Ambli; Xu, Xiaoli (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
      Disease resistance of fish larvae may be improved by bath treatment in water containing immunostimulants. Pattern recognition receptors, such as TLR3, TLR7, and MDA5, work as an “early warning” to induce intracellular signaling and facilitate an antiviral response. A single bath of newly hatched larvae, with Astragalus, upregulated the expression of IFNα, IFNc, ISG15, MDA5, PKR, STAT1, TLR3, and ...

    • A new IL6 isoform in Chinese soft-shelled turtle (Pelodiscus sinesis) discovered: Its regulation during cold stress and infection 

      Zhang, Zuobing; Tian, M.; song, r; Xing, X; Fan, Y; Wang, L; Niu, C; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-25)
      The Chinese soft-shelled turtle (<i>Pelodiscus sinesis</i>) is a widely cultured commercial species in East and Southeast Asian countries. The turtles frequently suffer from acute cold stress during farming in China. Stress-induced factor such as Interleukin-6 (IL6) is a multifunctional molecule that plays important roles in innate and adaptive immune response. In the present study, we found that ...

    • Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture 

      Zhang, Zuobing; Chi, Heng; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-25)
      The general understanding has been that only adaptive immunity is capable of immunological memory, but this concept has been challenged in recent years by studies showing that innate immune systems can mount resistance to reinfection—as the innate immune system can adapt its function following an insult. Innate immune training offers an attractive approach in intensive fish larval rearing, especially ...

    • Transcription factor T-bet in Atlantic salmon: characterization and gene expression in mucosal tissues during Aeromonas salmonicida infection 

      Kumari, Jaya; Zhang, Zuobing; Swain, Trilochan; Chi, Heng; Niu, Cuijuan; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-06)
      The T-box transcription factor T-bet is expressed in a number of hematopoietic cell types in mammals and plays an essential role in the lineage determination of Th1 T-helper cells and is considered as an essential feature for both innate and adaptive immune responses in higher vertebrates. In the present study, we have identified and characterized the full-length Atlantic salmon T-bet cDNA (3502 ...